Endocrine Abstracts

Introduction: Neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disorder that cause a growth of noncancerous tumors in the nervous system, it associates cranial schwannomas, meningiomas, and skin and ophthalmologic lesions. It is a rare condition and its association with an intrasellar arachnoidocele has not been reported yet. We report the case of a patient who presents a NF2 associated with hypopituitarism related to an intrasellar arachnoidocele.<p class="...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of childbearing age. This condition combines, according to the diagnostic criteria of the Rotterdam consensus 2003, clinical and/or biochemical signs of hyperandrogenism, oligo- and/or anovulation and polycystic ovaries detected by ultrasound. Thyroid diseases are also frequent in the general population. The aim of our study was to determine the prevalence of thyroid ultrasound alterations in...

Introduction: Adrenal insufficiency is defined as a deficit in the functioning of the adrenal cortex. The acute form represents a diagnostic and therapeutic emergency, but the clinical presentation is sometimes misleading.Observation: We report the case of a 57-year-old patient with a personal history of vitiligo, who was suffering for two months from asthenia with abdominal pain and vomiting, then he presented with a generalized tonic-clonic convulsive ...

Introduction: Primary hyperparathyroidism is an asymptomatic endocrine disorder in 80% of the cases. The bone manifestation represents the late stage of the disease and the brown tumor represents an exceptional and rare lesion.Observation: We report the case of a 73-year-old patient, with a medical history of type 2 diabetes, followed in the oto-rhino-laryngology department for a gingival tumor. A biopsy was performed and the anatomopathological examinat...

Introduction: Wermer syndrome or multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary disease characterized by the presence of generally benign tumors of the endocrine glands.Observation: We report the case of a 68-year-old patient with a family history of a sister having a primary hyperaldosteronism and a personal history of primary hyperaldosteronism who was referred to our department for the exploration of asymptomatic hypercalcemia. The bi...

IntroductionPremature ovarian insufficiency (POI) is characterized by the loss of ovarian activity before the age of 40. It is associated with hypoestrogenism, raised gonadotrophins and oligomenorrhea or amenorrhea. POI is a heterogeneous disease that can result from different etiologies, including genetic, autoimmune, and iatrogenic. Of the genetic causes, single-gene mutations and chromosomal imbalances involving X chromosome or autosomes have been ass...

IntroductionGraves ophthalmopathy (GO) is an inflammatory autoimmune disorder of the orbit which is associated with autoimmune thyroid disease. The medical treatment of severe and sight threatening GO remains a challenge, it generally implies the use of glucocorticoids with others treatments. Mycophenolate mofetil (MMF) is a prodrug of mycophenolic acid that prevents T-cell and B-cell proliferation and the production of cytotoxic T-cells and antibodies. ...

IntroductionHematological abnormalities are frequently observed in hyperthyroidism and are part of complex, multifactorial pathogenetic mechanisms that are still poorly understood, which can affect the three hematopoietic lineages in isolation or in combination. For the endocrinologist, they raise the issue of the risk of their aggravation under the hamatotoxic effect of antithyroid drugs (ATDs).Case presentation<p class="abste...

IntroductionPrimary adrenal lymphoma (PAL) are rare extranodal lymphomas and account for<1% of all non-Hodgkin lymphomas, with characteristic clinical features including high incidence of bilateral involvement, predominantly diffuse large B-cell histology, and low incidence of extra-adrenal disease at diagnosis. We report a case of 50-year-old patient affected by bilateral B-cell adrenal lymphoma.Case presentation<p class="...

IntroductionDiabetes is a chronic disease and a public health problem. Insulin Injection is used as a treatment for type 1 diabetes and insulin-requiring type 2 diabetes. A well-made injection is the key to a good glycemic balance. However, many studies showed that diabetic patients did not master the injection technique, reflecting an empirical random or non-existent therapeutic patient education(TPE). Our objectives were to assess our patients’ kn...